ea0007p179 | Reproduction | BES2004
Rae M
, Ross A
, Niven D
, Critchley H
, Ghazal P
, Lathe R
, Hillier S
IntroductionOvulation involves rupture of the ovarian surface, and thus the ovarian surface epithelium (OSE) is subjected to serial injury and repair with each ovulatory cycle. Inflammation is integral to the process of ovulation, but importantly, inflammatory damage is also thought to be a potential mechanism of ovarian tumour development. We have examined OSE responses to an inflammatory stimulus associated with ovulation, Interleukin-1alpha (IL1alpha)...